Lycium barbarum Polysaccharides Promote Maturity of Murine Dendritic Cells through Toll-Like Receptor 4-Erk1/2-Blimp1 Signaling Pathway

Figure 7

LBP induces the expression of TLR4, Erk1/2, and Blimp1 in DCs from a mouse spleen in vivo study. Both LBP (0, 10, 20, and 40 mg/kg) and LPS (1 mg/kg) were administered intraperitoneally to C57BL/6 mice in three groups. After 7 days, mouse splenic DCs were isolated and examined for TLR4 (b), Erk1/2 (c), and Blimp1 (d) expression by Western blot. Values are the mean and SD of 5 independent experiments. , and , and versus control.

(a)

(b)

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(d)