Differential Immunogenicity and Protective Efficacy Elicited by MTO- and DMT-Adjuvanted CMFO Subunit Vaccines against Mycobacterium tuberculosis Infection

Figure 4

Short-term and long-term protection efficacies between different vaccinated groups. Vaccination and challenge schedule. At the 14th (a) and 24th weeks (b), bacterial load in the lung and spleen per organ was enumerated. The results were shown as the log₁₀ CFU (). Representative histopathological photographs of the lung and lung histopathological score () from short-term and long-term experiments were also provided. HE staining, and AF staining, . Arrowheads indicate AF positive bacteria. .

(a)

(b)