After Treatment Decrease of Bone Marrow Tregs and Outcome in Younger Patients with Newly Diagnosed Acute Myeloid Leukemia

Table 1

Patients’ characteristics.

Age
Median value, range	56 (19-65)
Sex, (%)
Male	18 (46)
Female	21 (54)
AML FAB classification, (%)
M0	6 (15)
M1	7 (18)
M2	11 (28)
M4	9 (24)
M5	6 (15)
WBC/μL
Median value (range)	17000 (1400-281000)
Molecular/cytogenetics^@, (%)
Good	3 (8)
Intermediate	26 (66)
Poor	10 (26)
NPM1 mutated, (%)	8 (20)
FLT3 mutated, (%)
ITD	7 (18)
D835	2 (5)
dBMA Tregs
Median value (range)	14 (2-82)
Secondary AML, (%)	6 (15)
Overall response, (%)	21 (54)

^@according to ELN 2010 [ITD allelic ratio not performed]. AML: acute myeloid leukemia; ITD: internal tandem duplication; FAB: French-American-British classification; WBC: white blood cells; dBMA Tregs: diagnostic bone marrow aspirate T regulatory cells.