miRNA-451a and miRNA-125a Expression Levels in Ankylosing Spondylitis: Impact on Disease Diagnosis, Prognosis, and Outcomes

Table 1

Comparison between the three studied groups according to different parameters.

	Active AS ()	Inactive AS ()	Controls ()
Age (years)
				0.087
Sex
Male	20 (69%)	20 (76.9%)	33 (60%)	0.304
Female	9 (31%)	6 (23.1%)	22 (40%)
Occupation
Working	19 (65.5%)	19 (73.1%)	38 (69.1%)	0.832
Not working	10 (34.5%)	7 (26.9%)	17 (30.9%)
Smoking
Smoker	13 (44.8%)	9 (34.6%)	10 (18.2%)	0.030
Non smoker	16 (55.2%)	17 (65.4%)	45 (81.8%)
MicroRNA-125a				<0.001
Sig.bet.Grps	, 01,
MicroRNA-451a				<0.001
Sig.bet.Grps	, ,
Diseases duration			–	0.005
BASDAI	5 ± 0.7	2.6 ± 0.8	–	<0.001
BASFI	4.7 ± 1.0	2.5 ± 0.7	–	<0.001
BASMI	4.6 ± 0.5	2.4 ± 0.6	–	<0.001
MSASSS	31 ± 2	17.6 ± 2.1	–	<0.001
Nonstructural damage (≤20)	(0 0%)	23 (88.5%)	–	<0.001
Structural damage (>20)	29 (100%)	3 (11.5%)	–
ASQoL			–	<0.001
VAS			–	<0.001
ESR				<0.001
Sig.bet.Grps	, ,
CRP				<0.001
Sig.bet.Grps	, ,
Vitamin D				<0.001
Sig.bet.Grps	, ,
HLAB-27	20 (69%)	16 (61.5%)	–	0.563

: number; BASDAI: Bath AS disease activity index; BASFI: Bath AS functional index; BASMI: Bath AS metrology index; VAS: visual analog scale; MSASSS: modified stroke ankylosing spondylitis spinal score; ASQoL: ankylosing spondylitis quality of life questionnaire; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; : value for comparing between the studied groups; : value for comparing between active AS and inactive AS; : value for comparing between active AS and controls; : value for comparing between inactive AS and controls. Statistically significant at .