Identifying 4 Novel lncRNAs as Potential Biomarkers for Acute Rejection and Graft Loss of Renal Allograft

Figure 7

Pearson correlation analysis between the 4 lncRNAs and 5 common different allograft-infiltrating immune cell types. (a, b) CIBERSORT estimation of 22 immune cell types between AR and nonrejection specimens in the merged dataset and GSE76882 dataset, respectively. CD8⁺ T cells, activated memory CD4⁺ T cells, gamma delta T cells, resting dendritic cells, and eosinophils are 5 significantly different immune cell types common to the merged dataset and GSE76882 dataset. (c) The correlation between the expression of ATP1A1-AS1 and gamma delta T cells as well as eosinophils. (d) The correlation between the expression of CTD-3080P12.3 and gamma delta T cells as well as eosinophils. (e) The correlation between the expression of EMX2OS and gamma delta T cells as well as eosinophils. (f) The correlation between the expression of LINC00645 and CD8⁺ T cells as well as resting dendritic cells. CIBERSORT: cell type identification by estimating relative subsets of RNA transcripts; AR: acute rejection.

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