Research Article

Epitope-Based Peptide Vaccine against Glycoprotein G of Nipah Henipavirus Using Immunoinformatics Approaches

Table 4

A population coverage for all epitopes that bind to MHC classes I and II alleles from different parts of the world.

MHC classesPopulationWorldSouth AsiaSoutheast AsiaSudanNorth Africa

Class ICoveragea99.84%98.40%98.55%99.36%99.23%
Average_hitb36.6230.6028.4234.0232.43
PC90c16.879.298.6113.4012.95

Class IICoveragea56.84%56.0%48.63%55.75%62.37%
Average_hitb54.8850.5036.2736.8950.09
PC90c-24.24-10.091.654.60-3.31

aProjected population coverage; baverage number of epitope hits/HLA combinations recognized by the population; cminimum number of epitope hits/HLA combinations recognized by 90% of the population.