Single Nucleotide Polymorphisms in TLR4 Affect Susceptibility to Tuberculosis in Mexican Population from the State of Veracruz

Table 3

Analysis of haplotypes association with active TB.

Haplotype	Frequency	Case frequency	Control frequency	OR (95% CI)	value
Chromosome 4
CCCG	0.53	0.53	0.53	1.02 (0.83-1.26)	0.85
CCTG	0.21	0.22	0.21	1.02 (0.79-1.31)	0.88
TATG	0.17	0.16	0.17	0.98 (0.74-1.30)	0.91
CCTA	0.06	0.07	0.06	1.27 (0.83-1.93)	0.25
TACG	0.01	0.01	0.01	0.73 (0.20-2.15)	0.54
Chromosome 9
AC	0.98	0.99	0.97	3.51 (1.36-11.53)	0.006
GT	0.02	0.01	0.02	0.35 (0.09-1.03)	0.043

Chromosome 4: TLR10 A163S, TLR10 V298I, TLR1 N248S, TLR6 S249P; chromosome 9: TLR4 D299G, TLR4 T399I.