Wogonin Suppresses IL-10 Production in B Cells via STAT3 and ERK Signaling Pathway

Figure 3

Effect of Wogonin on the surface molecules of B cells. CD19⁺ cells were cultured with LPS in the presence of 12.5 μM Wogonin for 24 h and 48 h to analyze the surface marker levels. (a, b) The expression levels of CD5, CD24, CD21, CD38, CD23, MHCII, IgM, IgD, CD80, and CD86 in untreated B cells (black), LPS-treated B cells (red), and LPS+Wogonin-treated B cells (blue) were measured by FACS, respectively. (c) Quantification of B cell surface molecules. Data are expressed as of three independent experiments. ; ; ; ns: no significance.

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