Integrated Bioinformatics Analysis Identifies ELAVL1 and APP as Candidate Crucial Genes for Crohn’s Disease

Figure 4

NOD-like receptor signaling pathway is enriched in the blood of CD by GSE analysis. (a) GSEA-generated heatmaps of core enrichment genes in the NOD-like receptor signaling pathway upregulated in CD patients of three datasets. (b–d) Enrichment maps were used for the visualization of NOD-like receptor signaling pathway enrichment results separately. (e) Integrated enrichment network of the three microarray datasets was generated by NetworkAnalyst. (f) Enrichment map visualizes NOD-like receptor signaling pathway enrichment results from integrated data.

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