Analysis of the Heterogeneity of CD4⁺CD25⁺ T Cell TCR β CDR3 Repertoires in Breast Tumor Tissues, Lung Metastatic Tissues, and Spleens from 4T1 Tumor-Bearing BALB/c Mice

Figure 6

Total overlapped CDR3 sequences among breast tumor tissues, metastatic lung tissues, and spleens from three 4T1 tumor-bearing BALB/c mice (total of nine tissues) (a); statistical analysis comparison of the ratio of cloning proliferation of eight CDR3 sequences overlapping in nine tissues from the CDR3 repertoires: comparison of the three kinds of tissues (b); single comparison (c, d) (Supplement Table 1, , , , ); the distribution and proportion statistical analysis of the top 20 sequences overlapping in the three tissues were compared (e, f).

(a)

(b)

(c)

(d)

(e)

(f)