Research Article
Kangtaizhi Granule Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats and HepG2 Cells via AMPK/mTOR Signaling Pathway
Figure 5
Effect of KTZG on PPAR-γ, SREBP-1, p-AKT, FAS, SIRT1, and AMPK/mTOR signaling pathway in HFD fed rats. (a) Western blotting for PPAR-γ, SREBP-1, and p-AKT in HFD-fed liver tissues treated with KTZG. (b) Western blotting for p-AMPK, AMPK, p-mTOR, and mTOR in HFD-fed liver tissues treated with KTZG. (c) Immunohistochemical of FAS and SIRT1 in liver tissues (magnification ×200). Compared to control group, ▲, ▲▲; compared to NAFLD group, ★, ★★.
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