Research Article
Clinical Characteristics of Peripheral Neuropathy in Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Single-Center Study in China
Table 2
Comparison of baseline features between EGPA patients with PN and without PN.
| Characteristics | With PN
| Without PN
| value |
| Demographics | | | | Age (year, x ± S) | 47±12.9 | 43±14.0 | 0.096 | Gender (male/female, n) | 27/24 | 33/26 | 0.753 | Time from allergy to EGPA diagnosis (month), median (IQR) | 24(3,84) | 24(6,62) | 0.942 | Disease duration(month), median (IQR) | 7(2,19) | 4(2,15) | 0.308 | Time from initial symptoms to EGPA diagnosis (month), median (IQR) | 12(0,48) | 6 (0,42) | 0.423 | Clinical manifestation [n (%)] | | | | Weight loss | 25(49.0) | 16(27.1) | 0.018 | Fever | 24(47.1) | 21(35.6) | 0.223 | Arthritis or joint pain | 12(23.5) | 5(8.5) | 0.029 | Myalgia | 14(27.5) | 8(13.6) | 0.069 | Allergic rhinitis | 15(29.4) | 25(42.4) | 0.159 | Asthma | 40(78.4) | 45(76.3) | 0.787 | Cutaneous vasculitis | 26(51.0) | 33(55.9) | 0.604 | Renal involvement | 16(31.4) | 12(20.3) | 0.185 | Digestive tract involvement | 20(39.2) | 16(27.1) | 0.178 | CNS involvement | 11(21.6) | 8(13.6) | 0.268 | Heart involvement | 20(39.2) | 20(33.9) | 0.563 | Ear involvement | 8(15.7) | 6(10.2) | 0.387 | Sinusitis | 29(56.9) | 35(59.3) | 0.794 | Eos count (×109/L), median (IQR) | 3.3(1.3,9.1) | 2.7(1.3,5.8) | 0.827 | Clinical score | | | | BVAS [recent 4 weeks, median (IQR)] | 18(14,22) | 12(8,16) | <0.0001 | FFS ≥1[n (%)] | 31(60.8) | 25(42.4) | 0.054 |
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PN: peripheral neuropathy; CNS: Central Nervous System; Eos: eosinophil; BVAS: Birmingham Vasculitis Activity Score; FFS: five factor score; . |