Research Article

Clinical Characteristics of Peripheral Neuropathy in Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Single-Center Study in China

Table 2

Comparison of baseline features between EGPA patients with PN and without PN.

CharacteristicsWith PN
Without PN
value

Demographics
Age (year, x ± S)47±12.943±14.00.096
Gender (male/female, n)27/2433/260.753
Time from allergy to EGPA diagnosis (month), median (IQR)24(3,84)24(6,62)0.942
Disease duration(month), median (IQR)7(2,19)4(2,15)0.308
Time from initial symptoms to EGPA diagnosis (month), median (IQR)12(0,48)6 (0,42)0.423
Clinical manifestation [n (%)]
Weight loss25(49.0)16(27.1)0.018
Fever24(47.1)21(35.6)0.223
Arthritis or joint pain12(23.5)5(8.5)0.029
Myalgia14(27.5)8(13.6)0.069
Allergic rhinitis15(29.4)25(42.4)0.159
Asthma40(78.4)45(76.3)0.787
Cutaneous vasculitis26(51.0)33(55.9)0.604
Renal involvement16(31.4)12(20.3)0.185
Digestive tract involvement20(39.2)16(27.1)0.178
CNS involvement11(21.6)8(13.6)0.268
Heart involvement20(39.2)20(33.9)0.563
Ear involvement8(15.7)6(10.2)0.387
Sinusitis29(56.9)35(59.3)0.794
Eos count (×109/L), median (IQR)3.3(1.3,9.1)2.7(1.3,5.8)0.827
Clinical score
BVAS [recent 4 weeks, median (IQR)]18(14,22)12(8,16)<0.0001
FFS ≥1[n (%)]31(60.8)25(42.4)0.054

PN: peripheral neuropathy; CNS: Central Nervous System; Eos: eosinophil; BVAS: Birmingham Vasculitis Activity Score; FFS: five factor score; .