Research Article

Higher Serum CCN3 Is Associated with Disease Activity and Inflammatory Markers in Rheumatoid Arthritis

Table 1

Baseline characteristics of participants in this study.

CharacteristicsRA patientsHealthy controls

Total (female/male)41 (36/5)45 (37/8)
Age, mean (SD) (year)51.7 (16.3)49.6 (12.1)
Duration of disease, mean (SD) (year)6.2 (5.6)
DAS28 (CRP), mean (SD)4.4 (1.6)
DAS28 (ESR), mean (SD)4.7 (1.7)
CRP (mg/l), mean (SD)57.5 (61.2)4.9 (3.8)
ESR (mm/h), mean (SD)49.9 (31.0)11.3 (9.6)
RF (IU/ml), mean (SD)580.2 (950.2)16.2 (10.9)
Anti-CCP (RU/ml), mean (SD)66.9 (63.8)12.4 (8.1)
IgG (g/l), mean (SD)14.5 (3.4)13.8 (6.4)
IgA (g/l), mean (SD)3.3 (1.3)3.0 (1.7)
IgM (g/l), mean (SD)1.5 (0.7)1.1 (2.0)
WBC (109/l), mean (SD)7.8 (2.4)6.9 (4.2)
Lym (109/l), mean (SD)1.8 (0.6)1.9 (1.1)
PLT (109/l), mean (SD)347.9 (102.3)196.3 (85.3)
Hb (g/l), mean (SD)111.2 (14.6)145.5 (21.8)

CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; RF: rheumatoid factor; anti-CCP: anti-cyclic citrullinated peptide; Ig: immunoglobulin; WBC: white blood cell; Lym: lymphocytes; PLT: platelet; Hb: hemoglobin. indicates RA vs. healthy controls (HC), . indicates RA vs. HC, . indicates RA vs. HC, .