Research Article

Thymic Stromal Lymphopoietin Is Implicated in the Pathogenesis of Bullous Pemphigoid by Dendritic Cells

Figure 4

Langerin-positive LCs infiltrated in the skin of patients with BP and HCs without difference. (a) Staining with langerin (green) and DAPI (blue); langerin-positive LCs (white arrowheads) infiltrated in the epidermis of the lesional skin in patients with BP. (b) Langerin-positive LCs (white arrowhead) also infiltrated in the epidermis of the HCs’ skin. Results from three patients with BP and three HCs are shown in (a, b), respectively. Dashed white lines indicate the basement membrane zone or edge of blister. Asterisks () indicate the area of blisters. Original magnification: ×100 and ×200, . BP: bullous pemphigoid; DAPI: 4,6-diamino-2-phenyl indole; HCs: healthy controls; LCs: Langerhans cells.
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