Potential Biomarkers of Peripheral and Central Fatigue in High-Intensity Trained Athletes at High-Temperature: A Pilot Study with Momordica charantia (Bitter Melon)

Table 6

Changes in central fatigue parameters during summer season training before and after MCE supplementation.

Variable	Before exercise	During exercise	After exercise	Msorning after exercise
Serotonin (ng/mL)
Pre					T	12.791^$$
Post					S	11.117^$$
-value	0.653	2.468	1.316	1.051		3.134^$
Dopamine (ng/mL)
Pre					T	1.327
Post					S	5.186^$
-value	1.130	2.985	0.662	-0.174		0.954
Prolactin (ng/mL)
Pre					T	0.610
Post					S	6.830^$
-value	1.407	3.438	2.577	1.246		4.652^$

Values are mean and standard deviation. , compared to the before-MCE supplementation values, ^#, ^##, ^### compared to the rest values. T: time effect; S: supplementation effect; : interaction effect, ^$, ^$$.