Interferon Kappa Is Important for Keratinocyte Host Defense against Herpes Simplex Virus-1
Addition of rhIFNκ inhibits HSV-1 replication in NHEK. Undifferentiated (UD) and differentiated (D) NHEK cells were treated with rhIFNκ (10 ng/ml) and indicated MOI of HSV-1 for 24 hours. Cells were then harvested for real-time qRT-PCR. (a) IFNκ and (b) HSV-1 gD transcripts were evaluated by real-time qRT-PCR. (c) Representative viral plaque assay results were shown. (d) Quantitative results of HSV-1 plaque assays. Data presented as . One of three independent experiments is presented.
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