Galectin-3 Is a Potential Mediator for Atherosclerosis

Figure 2

Diagram depicting the mechanisms by which Gal-3 promotes formation of atherosclerosis. Gal-3: galectin-3; TNF-α: tumor necrosis factor-α; IL-6: interleukin-6; CXCL8: C-X-C motif chemokine 8; CCL2: C-C chemokine ligand 2; CCL3: C-C chemokine ligand 3; CCL5: C-C chemokine ligand 5; ox-LDL: oxidized low-density lipoprotein; VSMC: vascular smooth muscle cells; AGEs: advanced glycation end products; NADPH II: nicotinamide-adenine dinucleotide phosphate II.