Review Article

The Scribble Complex PDZ Proteins in Immune Cell Polarities

Figure 1

ABCP polarity complexes in mammalian epithelial cells. Protein complexes of the apicobasal epithelial cell polarity are illustrated. Crumbs is concentrated in the apical region, Par3 in the tight junction (TJ), and Scribble in the adherens junction (AJ) and basolateral region. hLgl localization is controlled by aPKC phosphorylation.