Review Article

The Scribble Complex PDZ Proteins in Immune Cell Polarities

Table 1

The human Scribble complex genes (source: https://www.ncbi.nlm.nih.gov/gene).

GeneOfficial nameChromosomal locationExonsAliasesTissue of expressionGene isoformsGeneID

ScribScribble planar cell polarity protein837CRIB1, SCRB11, Vartul, SCRIBColon, testis, skin, and kidney223513
Dlg1Discs large MAGUK scaffold protein 1335DLGH1, SAP-97, SAP97, dJ1061C18.1.1, hDlgThyroid, brain, and esophagus151739
Dlg2Discs large MAGUK scaffold protein 21145PPP1R58, PSD-93, PSD93, chapsyn-110Brain91740
Dlg3Discs large MAGUK scaffold protein 31326MRX, MRX90, NEDLG, PPP1R82, SAP102, XLMRBrain, colon, and thyroid31741
Dlg4Discs large MAGUK scaffold protein 41727PSD95, SAP-90, SAP90Brain61742
Dlg5Discs large MAGUK scaffold protein 51043LP-DLG, P-DLG5, PDLGPlacenta, skin, adrenal glands, and thyroid19231
Llgl1LLGL1, scribble cell polarity complex component1723DLG4, HUGL, HUGL1, LLGL, Lgl1, Mgl1Brain, testis, ovaries, and endometrium13996
Llgl2LLGL2, scribble cell polarity complex component1731HGL, Hugl-2, LGL2Colon, stomach, and small intestine33993