Urinary System Manifestation of IgG4-Related Disease: Clinical, Laboratory, Radiological, and Pathological Spectra of a Chinese Single-Centre Study
Table 2
Baseline laboratory features of primary IgG4-RUD patients.
TIN ()
MN ()
Renal pelvis+ureter ()
Abnormal radiology ()
Parenchymal+retroperitoneal fibrosis ()
value
Alb, g/L (IQR)
37.0 (27.0-42.0)
18.0 (14.0-25.0)
40.5 (36.3-47.0)
40.0 (35.5-40.8)
37.0 (29.3-42.8)
0.006
SCr, μmol/L (IQR)
151.5 (78.3-256.8)
75.0 (59.0-127.5)
67.0 (63.0-78.5)
60.0 (58.0-77.0)
502.0 (231.5-720.0)
<0.001
24hUP, g/24 h (IQR)
0.68 (0.35-1.41)
11.13 (6.27-16.75)
0.99 (0.68-1.27)
0.002
IgG, g/L (IQR)
29.4 (19.3-41.5)
14.6 (8.9-28.7)
19.4 (11.9-37.2)
19.9 (16.0-31.1)
19.6 (17.0-32.7)
0.395
IgE, KU/L (IQR)
555.5 (341.8-913.8)
1469.0 (632.5-1943.0)
357.0 (90.7-824.3)
404.5 (100.2-649.8)
187.0 (68.6-1426.5)
0.479
IgG1, mg/L (IQR)
12400 (9020-15500)
5640 (2720-9635)
8840 (8310-12950)
8695 (6690-10993)
9110 (8730-14400)
0.015
IgG2, mg/L (IQR)
6345 (5058-8628)
3910 (3425-5045)
5440 (3840-7280)
5510 (5093-9583)
5580 (2950-7965)
0.228
IgG3, mg/L (IQR)
753 (368-1380)
154 (127-701)
678 (382-898)
525 (287-1100)
729 (434-1558)
0.193
IgG4, mg/L (IQR)
17500 (10536-30950)
10270 (8310-12950)
7920 (3058-38150)
9510 (4295-15050)
14100 (3200-22000)
0.422
ESR, mm/h (IQR)
50 (15-91)
78 (46-85)
29 (13-58)
21 (6-38)
81 (57-94)
0.046
hsCRP, mg/L (IQR)
5.92 (0.77-18.62)
2.67 (1.62-11.07)
2.14 (0.93-4.15)
1.91 (0.39-4.73)
6.07 (3.75-23.16)
0.206
C3, g/L (IQR)
0.482 (0.430-0.739)
0.579 (0.426-0.867)
0.954 (0.854-1.062)
0.781 (0.477-1.101)
0.928 (0.693-1.134)
0.033
C4, g/L (IQR)
0.065 (0.028-0.145)
0.208
0.176 (0.136-0.267)
0.205 (0.036-0.260)
0.233 (0.122-0.282)
0.051
We did not analyse IgG4-TIN+GN patients to avoid misleading data for Alb, SCr, and 24hUP. Data from the only patient with IgG4-related bladder involvement are also not listed in the chart above. 24-hour urine protein levels were not quantified due to negative routine urine tests.
