Research Article
Th1/Th2 Cells and Associated Cytokines in Acute Hepatitis E and Related Acute Liver Failure
Table 1
Characteristics of study subjects.
| | HC group () | AHE group () | HEV-ALF group () | value |
| Age (y) | | | | 0.018 | Gender (F/M) | 9/8 | 7/10 | 3/14 | 0.095 | Pregnant woman | 0 | 0 | 0 | — | Fever | 0 | 4 (23.53) | 7 (41.18) | 0.014 | Jaundice | 0 | 15 (88.24) | 17 (100.00) | ≤0.001 | Nausea/vomit | 0 | 5 (29.41) | 9 (52.94) | 0.002 | Severity of hepatic encephalopathy | 0 | 0 | 4 (23.53) | 0.013 | Hepatorenal syndrome | 0 | 2 (11.76) | 1 (5.88) | 0.352 | Ascites | 0 | 2 (11.76) | 8 (47.06) | ≤0.001 | IgM(+) | 0 | 17 (100.00) | 17 (100.00) | ≤0.001 | HEV-RNA (IU/ml) | 0 | 34.84 (29.18-38.73) | 33.44 (30.55-37.74) | ≤0.001 | ALT (U/l) | 18 (9-31) | 535 (128-834) | 750 (392-1027) | ≤0.001 | TBIL (μmol/l) | 12.4 (8.4-14.2) | 58.0 (12.2-141.6) | 206.6 (92.0-263.4) | ≤0.001 | Length of stay (day) | 0 | 7 (5-11) | 12 (8-23) | ≤0.001 | Mortality rate | 0 | 0 | 8 (47.06) | ≤0.001 |
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The value was for the difference among the three groups. |