Research Article
Prealbumin-to-Globulin Ratio Can Predict the Chemotherapy Outcomes and Prognosis of Patients with Gastric Cancer Receiving First-Line Chemotherapy
Table 1
Baseline characteristics of the patients.
| Characteristics | Cases () | Percentage |
| Sex | | | Male | 187 | 66.55% | Female | 94 | 33.45% | Age (yr) | | | ≤60 | 159 | 56.58% | >60 | 122 | 43.42% | Body mass index (kg/m2) | | | <18.5 or >25 | 72 | 25.62% | 18.5–25 | 209 | 74.38% | ECOG | | | 0–1 | 233 | 82.92% | ≥2 | 48 | 17.08% | Histological type | | | Papillary, tubular, | 73 | 25.98% | Poorly cohesive, mucinous | 208 | 74.02% | TNM stage | | | III | 55 | 19.57% | IV | 226 | 80.43% | Number of organs affected by metastasis | | | 0–1 | 190 | 67.62% | ≥2 | 91 | 32.38% | Peritoneal metastasis | | | Yes | 91 | 32.38% | No | 190 | 67.62% | First-line chemotherapy regimen | | | SOX/CapeOX | 142 | 50.53% | FOLFOX | 49 | 17.44% | DCF/DOF | 30 | 10.68% | Capecitabine/S-1 | 22 | 7.83% | Others | 38 | 13.52% | Best response | | | Complete remission | 0 | — | Partial response | 37 | 13.17% | Stable disease | 205 | 72.95% | Progression of disease | 39 | 13.88% | Objective response rate | 37 | 13.17% | Disease control rate | 242 | 86.12% | Tumor biomarkers | | | CEA >5 ng/mL | 121 | 43.06% | CA72-4 >6 U/mL | 158 | 56.23% | CA19-9 >37 U/mL | 106 | 37.72% | Hemoglobin (g/L) | | | <115 | 105 | 37.37% | ≥115 | 176 | 62.63% | Albumin (g/L) | | | <35 | 52 | 18.51% | ≥35 | 229 | 81.49% | Prealbumin (mg/L) | | | <160 | 83 | 29.54% | ≥160 | 198 | 70.46% | Globulin (g/L) | | | ≤35 | 259 | 92.17% | >35 | 22 | 7.83% | PGR | | | <7.21 | 139 | 49.47% | ≥7.21 | 142 | 50.53% | AGR | | | <1.46 | 128 | 45.55% | ≥1.46 | 153 | 54.45% |
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ECOG: Eastern Cooperative Oncology Group; TNM: tumor-node-metastasis; SOX: oxaliplatin + S1; CapeOX: oxaliplatin + capecitabine; FOLFOX: oxaliplatin + leucovorin + 5-fluorouracil; DCF: docetaxel + cisplatin + 5-fluorouracil; DOF: docetaxel + oxaliplatin + 5-fluorouracil; CEA: carcinoembryonic antigen; CA72-4: carbonhydrate antigen 72-4; CA 19-9: carbonhydrate antigen 19-9; PGR: prealbumin-to-globulin ratio; AGR: albumin-to-globulin ratio.
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