The Immunosuppressant Fingolimod (FTY720) for the Treatment of Mechanical Force-Induced Abnormal Scars

Figure 1

Effect of topical FTY720 injection on the Day 14 T cell population in the scars. (a) Schematic depiction of the schedule in which mechanical force-induced hypertrophic scars were generated in mice and treated with FTY720 injections. (b) The frequencies of CD3⁺, CD3⁺CD4⁺, and CD3⁺CD8a⁺ T cells in the scars were determined by flow cytometry (). Two independent experiments were performed. Both showed similar results. All values shown represent

(a)

(b)