The Immunosuppressant Fingolimod (FTY720) for the Treatment of Mechanical Force-Induced Abnormal Scars

Figure 7

The effect of 2 μM FTY720 with 100 ng/ml LPS in RAW264.7 macrophages. (a) The expression of M1 and M2 marker genes was determined by qRT-PCR (). (b) Representative flow cytometric plots are shown along with the average frequencies of F4/80⁺ cells. The percentages of F4/80⁺ cells were determined by flow cytometry (). (c) Representative flow cytometric plots are shown along with the average frequencies of F4/80⁺CD206⁺ cells. The percentages of F4/80⁺ and F4/80⁺CD206⁺ cells were determined by flow cytometry (). Two independent experiments were performed. Both showed similar results. , as determined by Student’s -test or Welch’s -test after test.

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