HMGB1 Recruits TET2/AID/TDG to Induce DNA Demethylation in STAT3 Promoter in CD4⁺ T Cells from aGVHD Patients

Figure 1

HMGB1, TET2, AID, and TDG were detected in STAT3 promoter. ChIP-PCR showed that HMGB1, (a) TET2, (b) AID, and (c) TDG bound to the STAT3 promoter region (-813 bp to +683 bp).

(a)

(b)

(c)

(d)