Review Article

Protective Immunity against SARS Subunit Vaccine Candidates Based on Spike Protein: Lessons for Coronavirus Vaccine Development

Figure 1

Schematic structure of the spike protein. Abbreviations: SP: signal peptide; RBD: receptor-binding domain; RMB: receptor motif binding; FP: fusion peptide; HR1: heptad repeat domain 1; HR2: heptad repeat domain 2; TM: transmembrane domain; CP: cytoplasmic domain. Numbers indicate amino acid sequence.