Anti-Inflammatory Activity of Diterpenoids from Celastrus orbiculatus in Lipopolysaccharide-Stimulated RAW264.7 Cells

Table 1

¹H and ¹³C NMR spectroscopic data ( ppm) for compound 3.

Position	3
			( in Hz)
1	39.2	CH2	2.29, d (12.6)
			1.50, m
2	20.1	CH2	1.83^a, m
			1.67, br d (13.8)
3	42.7	CH2	1.55, d (13.2)
			1.32, td (13.2, 2.4)
4	34.3	C	—
5	51.4/51.3	CH	1.84^a, m
6	37.1/37.0	CH2	2.64, m
7	200.5	C	—
8	126.2/126.1	C	—
9	153.0/152.9	C	—
10	39.4/39.3	C	—
11	113.4/113.3	CH	6.94^a, s/6.93^a, s
12	151.2/151.1	C	—
13	143.6/143.5	C	—
14	116.4	CH	7.54, s/7.52, s
15	33.2	CH3	0.96^a, s/0.95ª, s
16	21.9	CH3	1.03, s
17	23.9/23.8	CH3	1.25^a, s/1.24^a, s
1’	129.0/128.9	C	—
2’	112.2/112.1	CH	7.00, d (1.8)
3’	149.4	C	—
4’	148.7	C	—
5’	116.5	CH	6.84, d (8.4)
6’	121.9	CH	6.90, dd (8.4, 1.8)
7’	78.7/78.6	CH	4.99, d (8.4)/4.97, d (8.4)
8’	80.0/79.9	CH	4.06, tdd (8.4, 4.2, 2.4)
9’	62.1	CH2	3.71, ddd (12.6, 2.4, 1.2)
			3.47, ddd (12.6, 4.2, 1.8)
OCH3-3’	56.6	CH3	3.88, s/3.87, s

Assignments were done by HSQC, HMBC, and COSY experiments. Spectra were measured in methanol-d₄ at 600 and 150 MHz. ^aOverlapped signals.