STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells
The STK3 expression in ovarian cancer cell lines. (a) Statistics of STK3-mutated samples derived from 683 patients in cBioportal. (b) The mRNA expression of STK3 was evaluated by real-time qPCR in cell lines (IOSE80, CAOV3, OVCAR3, and OVCAR8) treated with DMSO, DAC, TSA, or DAC plus TSA (two-tailed Student’s -test, ). (c) Total methylation rates of STK3 promoter in the human osteoblast cell line IOSE80 and three ovarian cancer cell lines (CAOV3, OVCAR3, and OVCAR8) are shown. (two-tailed Student’s -test, ,).
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