Journal of Immunology Research / 2020 / Article / Tab 1

Research Article

Single Nucleotide Polymorphisms in PPARD Associated with Systemic Lupus Erythematosus in Chinese Populations

Table 1

Association analysis of single nucleotide polymorphisms from PPARD gene with susceptibility to systemic lupus erythematosus in Chinese populations.

Chr.GeneSNPPosition (hg19)Minor alleleDiscovery stage (490/493)Replication stage (1003/815)Metaanalysis
MAF (case/control %) valueOR (95% CI)MAF (case/control %) valueOR (95% CI) valueOR (95% CI)

6PPARDrs226766435312254A36.7/28.61.45 (1.20-1.75)30.3/27.40.051.16 (1.00-1.34)1.24 (1.11-1.39)
6PPARDrs471385335327355C39.9/32.31.39 (1.16-1.68)34.9/31.50.031.17 (1.02-1.34)1.24 (1.11-1.38)

aThe value threshold with Bonferroni correction was less than 0.00294118 when considering 17 variants.

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