Circulating Monocytic Myeloid-Derived Suppressor Cells Are Elevated and Associated with Poor Prognosis in Acute Myeloid Leukemia

Table 1

Characteristics of 109 newly diagnosed patients with AML.

Group	Subgroup	Number	Group	Subgroup	Number
Gender	Male	62	Cross lineage	Yes	37
	Female	47		No	72
Age	<60 y (14-59)	58	Karyotype	Low risk	28
	≥60 y (60-91)	51		Medium risk	47
FAB classification	M0	1		High risk	15
	M1	4		No data	19
	M2	33	Fusion gene	RUNX1-RUNX1T1	9
	M3	19		PML/RARα	16
	M4	20		CBFβ-MYH11	5
	M5	9		Others	79
	M6	1	Gene mutation	FLT3-ITD	9
	Mu	22		CEBPA	6
WBC	Low	24		NMP1	5
	Middle	26		C-kit	3
	High	59		Others	86
AML type	De novo	93	First induction	CR	35
	Secondary	16		Non-CR	27
Extramedullar	Yes	13	Curative effect	CCR	27
	No	96		R/R	35

Note: AML: acute myeloid leukemia; FAB: Franch-American-Britain; Mu: unclassifiable AML in morphology; WBC: white blood cell; CR: complete remission; Non-CR: not complete remission; CCR: continued complete remission; R/R: relapse/refractory.