Research Article
Circulating Monocytic Myeloid-Derived Suppressor Cells Are Elevated and Associated with Poor Prognosis in Acute Myeloid Leukemia
Table 1
Characteristics of 109 newly diagnosed patients with AML.
| Group | Subgroup | Number | Group | Subgroup | Number |
| Gender | Male | 62 | Cross lineage | Yes | 37 | Female | 47 | | No | 72 | Age | <60 y (14-59) | 58 | Karyotype | Low risk | 28 | ≥60 y (60-91) | 51 | | Medium risk | 47 | FAB classification | M0 | 1 | | High risk | 15 | M1 | 4 | | No data | 19 | M2 | 33 | Fusion gene | RUNX1-RUNX1T1 | 9 | M3 | 19 | | PML/RARα | 16 | M4 | 20 | | CBFβ-MYH11 | 5 | M5 | 9 | | Others | 79 | M6 | 1 | Gene mutation | FLT3-ITD | 9 | Mu | 22 | | CEBPA | 6 | WBC | Low | 24 | | NMP1 | 5 | Middle | 26 | | C-kit | 3 | High | 59 | | Others | 86 | AML type | De novo | 93 | First induction | CR | 35 | Secondary | 16 | | Non-CR | 27 | Extramedullar | Yes | 13 | Curative effect | CCR | 27 | No | 96 | | R/R | 35 |
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Note: AML: acute myeloid leukemia; FAB: Franch-American-Britain; Mu: unclassifiable AML in morphology; WBC: white blood cell; CR: complete remission; Non-CR: not complete remission; CCR: continued complete remission; R/R: relapse/refractory.
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