Genetic Background of Hypertension in Connective Tissue Diseases

Table 4

Gene-to-gene interaction in hypertensive and normotensive groups with CTD and control groups.

Group	Genotype	CTD			Control
		WC
Normotensive	Pro12Pro		33	ns		49	ns
	Ala12/X		15			21
Hypertensive	Pro12Pro		41	0.0216		20	ns
	Ala12/X		15			13
Normotensive	C1431C		36	ns		45	ns
	T1431/X		12			25
Hypertensive	C1431C		43	ns		23	ns
	T1431/X		13			10
Normotensive	Trp64Trp		41	ns		64	ns
	Arg64/X		7			6
Hypertensive	Trp64Trp		45	ns		28	ns
	Arg64/X		11			5
BMI (kg/m^2)
Normotensive	Pro12Pro		33	ns		49	ns
	Ala12/X		15			21
Hypertensive	Pro12Pro		41	ns		20	ns
	Ala12/X		15			13
Normotensive	C1431C		36	ns		45	ns
	T1431/X		12			25
Hypertensive	C1431C		43	ns		23	ns
	T1431/X		13			10
Normotensive	Trp64Trp		41	ns		64	ns
	Arg64/X		7			6
Hypertensive	Trp64Trp		45	ns		28	ns
	Arg64/X		11			5

WC: waist circumference; BMI: body mass index; CTD: connective tissue diseases.