Retrospective Analysis of Adoptive TIL Therapy plus Anti-PD1 Therapy in Patients with Chemotherapy-Resistant Metastatic Osteosarcoma

Table 3

Characteristics of patients with ORR () and non-ORR ().

Characteristic	No. of ORR	No. of non-ORR	value
Gender
Male	14	26
Female	8	12	0.705
Age (years)
≥20	6	12
<20	16	26	0.726
ECOG PS
0	20	30
1	2	8	0.231
Site of primary tumor
Femur and tibia	12	26
Other	10	12	0.282
Size of primary tumor (cm)
≥5	17	31
<5	5	7	0.688
Response to neoadjuvant chemotherapy
Good	3	7
Poor	19	31	0.632
Location of metastasis
Lung	18	32
Others	4	6	0.811
Infusion of TIL numbers
≥	20	15
<	2	23	0.000
Infusion of CD8^+TIL percentage
≥60%	19	11
<60%	3	27	0.000
Infusion of CD8^+PD1^+TIL percentage
≥10%	4	21
<10%	18	17	0.005
Infusion of CD4^+FoxP3^+TIL percentage
≥20%	2	19
<20%	20	19	0.001