Tissue-Resident Type 2 Innate Lymphoid Cells Arrest Alveolarization in Bronchopulmonary Dysplasia

Figure 2

Cytokine levels and macrophages in lung increased markedly in BPD mice. (a, b) The expression of IL-4 and IL-13 in the lung on different postnatal days in saline and LPS groups, respectively, both vs. saline. (c) Representative FACS analysis showing the gating strategy to identify CD11b⁺F4/80⁺CD86⁺M1 and CD11b⁺F4/80⁺CD206⁺M2 macrophages in mouse lung. (d, e) Representative results of M1 and M2 macrophages detected by flow cytometry on different postnatal days in saline and LPS groups, respectively. (f, g) Percentage of M1 and M2 macrophages in the lung on different postnatal days in saline and LPS groups, respectively. Data are represented as . . The LPS group was compared with the saline group at the same time point, and indicates , indicates , indicates , and indicates .

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