Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review

Figure 2

(a–g) Immune cytokine/chemokine mediators statistically different reported in active TB, latent tuberculosis infection, and noninfected individuals in each sample type.

(a) RNA from antigen stimulated from whole blood cell pellets

(b) Plasma samples from whole blood—unstimulated

(c) Plasma samples from whole blood—stimulated

(d) PBMC culture supernatant—unstimulated

(e) PBMC culture supernatant—stimulated

(f) Blood culture supernatant

(g) Serum/plasma