Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review

Table 2

Substances evaluated for ability to differentiate people with active and latent tuberculosis and uninfected with TB.

Interleukins	IL-1, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-12 (p40/70), IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17, IL-17A, IL-17E, IL-17F, IL-18, IL-21, IL-22, IL-23, IL-25, IL-27, IL-28A, IL-31, IL-33
Growth factors	PDGF, PDGF-BB, EGF, PGF2α, FGF, TGF-α, TGF-β1, G-CSF, CSF2, CSF3, GM-CSF, VEGF, VEGF-A, SFC, β-NGF, basic FGF
Interferon	INF-γ, IFN-α, IFN-α2
Receptors	IL-1RA, IL-2R, sIL-2Rα, TNF-αR, IL-1R1, IL-1R2
Tumor necrosis factors	TNF-α, TNF-β, TNF-SF10 (TRAIL)
Alpha chemokines	CXCL5 (ENA-78), CXCL6 (GCP-2/LIX), CXCL8 (IL-8), CXCL9 (MIG), CXCL10 (IP-10), CXCL11 (I-TAC), CXCL12 (SDF-1α+β), CXCL13 (BCA-1)
Beta chemokines	CCL1 (I-309), CCL2 (MCP-1), CCL3 (MIP-1α), CCL4 (MIP-1β), CCL5 (RANTES), CCL7 (MCP-3), CCL8 (MCP-2), CCL11 (eotaxin), CCL13 (MCP-4), CCL15 (MIP-1δ), CCL17 (TARC), CCL20 (MIP-3α), CCL21 (6Ckine), CCL24 (eotaxin-2), CCL26 (eotaxin-3), CCL27 (CTACK)
Delta chemokines	CX3CL1 (fractalkine)
Others	ICAM-1 (CD54), sCD163, sCD14, sCD40L, I-TAG, MIF, LIF, LXA4, 15-Epi-LXA4