Elevated Levels of Activated and Pathogenic Eosinophils Characterize Moderate-Severe House Dust Mite Allergic Rhinitis

Figure 5

Blood eosinophils from subjects with moderate-severe allergic rhinitis produce more granule proteins. (a) Serum ECP and EPX levels in healthy controls, mild allergic rhinitis, and moderate-severe allergic rhinitis. (b) ECP and EPX release from blood eosinophils induced by CCL11. ECP: eosinophil cationic protein; EPX: eosinophil peroxidase; HC: healthy controls; M-AR: mild allergic rhinitis; MS-AR: moderate-severe allergic rhinitis.

(a)

(b)