Elevated Levels of Activated and Pathogenic Eosinophils Characterize Moderate-Severe House Dust Mite Allergic Rhinitis

Table 4

Demographic summary of subjects used in the in vitro eosinophil function study.

	Healthy controls	Mild AR	Moderate-severe AR	value
Total subjects,	4	4	4	—
Gender, male/female	2/2	2/2	2/2	—
Age (years)	22.5 (22, 25.25)	25.5 (22.75, 26.75)	25.5 (22, 30.5)	0.665
History of smoking (%)	0	0	0	—
SPT to Der p	Negative	Positive	Positive	—
Total IgE (KU/l)	29.3 (12.1, 46.5)	95.2 (87.5, 102.9)	180.1 (113.8, 246.4)	0.001
Specific IgE to Der p (KU/l)	0.05 (0.04, 0.06)	27.8 (10.95, 43.98)	76.35 (32.68, 94.3)	0.001

For continuous variables, data are expressed by medians and interquartile ranges. AR: allergic rhinitis; SPT: skin prick test; Der p: Dermatophagoides pteronyssinus; Ig: immunoglobulin.