TILs and Anti-PD1 Therapy: An Alternative Combination Therapy for PDL1 Negative Metastatic Cervical Cancer

Table 3

Characteristics of patients with ORR () and non-ORR ().

Characteristic	No. of ORR	No. of non-ORR	value
Age (years)
≥45	11	34
<45	9	26	0.896
Pathological type
Squamous cell	16	49
Adenocarcinoma	4	11	0.869
ECOG PS
0	13	37
1	7	23	0.790
Size of primary tumor (cm)
≥5	9	38
<5	11	22	0.149
First-line chemotherapy with bevacizumab
Yes	8	12
No	12	48	0.074
Location of metastatic tumors
Lung	11	45
Others	9	15	0.091
Infusion of TIL numbers
≥	17	10
<	3	50	0.000
Infusion of CD8^+ TIL percentage
≥60%	18	11
<60%	2	49	0.000
Infusion of CD8^+PD1^+ TIL percentage
≥10%	3	35
<10%	17	25	0.001
Infusion of CD4^+FoxP3^+ TIL percentage
≥20%	4	33
<20%	16	27	0.007
HPV status
Positive	20	48
Negative	0	12	0.030
Fever
Yes	20	34
No	0	26	0.000