Research Article

TILs and Anti-PD1 Therapy: An Alternative Combination Therapy for PDL1 Negative Metastatic Cervical Cancer

Table 5

Multivariate analysis (mPFS).

ParametersHazard ratio95% confidence interval value

Infusion of CD8+ TIL numbers (≥ vs. <)5.823(2.871, 11.81)<0.0001
Infusion of CD8+ TIL percentage (≥60% vs. <60%)7.05(2.813, 17.67)<0.0001
Infusion of CD8+PD1+ TIL percentage (≥10% vs. <10%)4.285(2.697, 6.807)<0.0001
Infusion of CD4+FoxP3+ TIL percentage (≥20% vs. <20%)4.551(2.74, 7.561)<0.0001
HPV status (positive vs. negative)11.84(1.915, 73.16)<0.0001
Fever (yes vs. no)6.857(2.83, 16.62)<0.0001