Research Article
Systemic Inflammation Response Index Predicts Survival Outcomes in Glioblastoma Multiforme Patients Treated with Standard Stupp Protocol
Table 3
Brain failure and survival outcomes per SIRI group.
| | Characteristic | All patients () | () | () | value |
| | Brain failure, (%) | | | | | | Present | 15 (8.2) | 11 (11.5) | 4 (4.7) | 0.014 | | Absent | 166 (91.8) | 85 (88.5) | 81 (95.3) | | | Brain failure pattern, (%) | | | | | | None | 15 (8.2) | 11 (11.5) | 4 (4.7) | 0.53 | | Infield | 140 (77.4) | 73 (76.0) | 67 (78.7) | | | Marginal | 14 (7.7) | 4 (4.2) | 10 (11.8) | | | Distant | 5 (2.8) | 3 (3.1) | 2 (2.4) | | | Infield and distant | 4 (2.2) | 3(3.1) | 1 (1.2) | | | Marginal and distant | 3 (1.7) | 2 (2.1) | 1 (1.2) | | | PFS | | | | | | Median, mo (95% CI) | 10.3 (7.2-13.4) | 16.2 (14.5-17.9) | 6.6 (3.1-8.9) | <0.001 | | 2 years (%) | 11.9 | 29.5 | 5.0 | | | 5 years (%) | 6.6 | 11.9 | 0 | | | OS | | | | | | Median, mo (95% CI) | 15.8 (12.5-19.1) | 22.9 (19.8-26.0) | 12.2 (9.7-14.6) | <0.001 | | 2 years, % | 27.2 | 44.6 | 5.5 | | | 5 years, % | 8.2 | 15.3 | 0 | |
|
|
Abbreviations: SIRI: systemic immune response index; CI: confidence interval; PFS: progression-free survival; OS: overall survival.
|
