Research Article
DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration
Table 1
Signaling pathways most significantly correlated with DHX37 expression based on their normalized enrichment score (NES) and
value.
| | GO name (BP) | NES | value | FDR | Positive | Protein localization to chromosome | 1.672 | ≤0.001 | 0.008 | | CENP-A containing chromatin organization | 1.665 | ≤0.001 | 0.004 | | rRNA metabolic process | 1.640 | ≤0.001 | 0.006 | | Chromosome localization | 1.635 | ≤0.001 | 0.005 | | Chromosome segregation | 1.634 | ≤0.001 | 0.004 | | DNA replication | 1.627 | ≤0.001 | 0.004 | Negative | Peroxisome organization | -1.916 | ≤0.001 | 0.107 | Benzene-containing compound metabolic process | -1.809 | ≤0.001 | 0.137 | Peroxisomal transport | -1.729 | ≤0.001 | 0.151 | Mitochondrial respiratory chain complex assembly | -1.721 | ≤0.001 | 0.119 | | GO name (CC) | NES | value | FDR | Positive | Preribosome | 2.404 | ≤0.001 | 0.000 | Condensed chromosome | 2.309 | ≤0.001 | 0.000 | Replication fork | 2.209 | ≤0.001 | 0.000 | Chromosomal region | 2.173 | ≤0.001 | 0.000 | Heterochromatin | 2.162 | ≤0.001 | 0.000 | Negative | NADH dehydrogenase complex | -2.478 | ≤0.001 | 0.000 | MHC protein complex | -2.371 | ≤0.001 | 0.000 | Respiratory chain | -2.251 | ≤0.001 | 0.000 | Platelet dense granule | -2.212 | ≤0.001 | 0.000 | Basal part of cell | -2.042 | ≤0.001 | 0.007 | | GO name (MF) | NES | value | FDR | Positive | snoRNA binding | 2.247 | ≤0.001 | 0.000 | tRNA binding | 2.233 | ≤0.001 | 0.000 | Helicase activity | 2.204 | ≤0.001 | 0.000 | Catalytic activity, acting on DNA | 2.161 | ≤0.001 | 0.000 | Methyl-CpG binding | 2.038 | ≤0.001 | 0.000 | Negative | Monooxygenase activity | -2.317 | ≤0.001 | 0.009 | Oxidoreductase activity, acting on NAD(P)H | -2.104 | ≤0.001 | 0.009 | Steroid dehydrogenase activity | -2.089 | ≤0.001 | 0.006 | Tetrapyrrole binding | -2.075 | ≤0.001 | 0.005 | Oxidoreductase activity, acting on peroxide as acceptor | -2.051 | ≤0.001 | 0.009 |
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