DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration

Table 1

Signaling pathways most significantly correlated with DHX37 expression based on their normalized enrichment score (NES) and value.

	GO name (BP)	NES	value	FDR
Positive	Protein localization to chromosome	1.672	≤0.001	0.008
	CENP-A containing chromatin organization	1.665	≤0.001	0.004
	rRNA metabolic process	1.640	≤0.001	0.006
	Chromosome localization	1.635	≤0.001	0.005
	Chromosome segregation	1.634	≤0.001	0.004
	DNA replication	1.627	≤0.001	0.004
Negative	Peroxisome organization	-1.916	≤0.001	0.107
	Benzene-containing compound metabolic process	-1.809	≤0.001	0.137
	Peroxisomal transport	-1.729	≤0.001	0.151
	Mitochondrial respiratory chain complex assembly	-1.721	≤0.001	0.119
	GO name (CC)	NES	value	FDR
Positive	Preribosome	2.404	≤0.001	0.000
	Condensed chromosome	2.309	≤0.001	0.000
	Replication fork	2.209	≤0.001	0.000
	Chromosomal region	2.173	≤0.001	0.000
	Heterochromatin	2.162	≤0.001	0.000
Negative	NADH dehydrogenase complex	-2.478	≤0.001	0.000
	MHC protein complex	-2.371	≤0.001	0.000
	Respiratory chain	-2.251	≤0.001	0.000
	Platelet dense granule	-2.212	≤0.001	0.000
	Basal part of cell	-2.042	≤0.001	0.007
	GO name (MF)	NES	value	FDR
Positive	snoRNA binding	2.247	≤0.001	0.000
	tRNA binding	2.233	≤0.001	0.000
	Helicase activity	2.204	≤0.001	0.000
	Catalytic activity, acting on DNA	2.161	≤0.001	0.000
	Methyl-CpG binding	2.038	≤0.001	0.000
Negative	Monooxygenase activity	-2.317	≤0.001	0.009
	Oxidoreductase activity, acting on NAD(P)H	-2.104	≤0.001	0.009
	Steroid dehydrogenase activity	-2.089	≤0.001	0.006
	Tetrapyrrole binding	-2.075	≤0.001	0.005
	Oxidoreductase activity, acting on peroxide as acceptor	-2.051	≤0.001	0.009