Review Article
The Role of Inflammation in Crohn’s Disease Recurrence after Surgical Treatment
Table 2
New perspectives for recurrence prevention.
| Domain | Prevention strategy | Description | Rationale |
| Medical | Fecal transplantation | Transfer of fecal bacteria from healthy subjects | Avoid dysbiosis reestablishment | Medical | Hematopoietic stem cell transplantation | Bone marrow ablation followed by autotransplantation of multipotent stem cells | Reset immune system | Surgical | Michelassi strictureplasty | Side-to-side isoperistaltic strictureplasty | Induce mucosal healing by resolution of chronic obstruction | Surgical | Kono anastomosis | Fashioning of antimesenteric wide lumen anastomosis | Increase the diameter and stability/durability of anastomosis | Surgical | Mesenteric excision | Excision of the associated mesentery | Removal of pathological tissue | Surgical | Pathophysiological excision | Excision of draining mesenteric lymph nodes | Removal of most memory T-cells, drivers of inflammation and recurrence |
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