Multiepitope Subunit Vaccine Design against COVID-19 Based on the Spike Protein of SARS-CoV-2: An In Silico Analysis

Figure 1

Here, the overall design of our study is shown. The sequence of SARS-CoV-2 spike protein was subjected to in silico epitope prediction and prioritization steps to select promiscuous T-cell epitopes. These epitopes were linked together to construct a multiepitope vaccine which was subjected to molecular docking analysis with TLR3. Based on these results, a multiepitope vaccine was proposed against COVID-19.