Research Article

Altered Regulatory B Cell Subsets in Children with Type 1 Diabetes Mellitus

Table 2

Correlations between B cell phenotypes and demographic, clinical and laboratory characteristics of the study patients.

VariableB cell phenotype
CD19+ total B cellsIL10+CD19+ (IL10 B cells)IL10+CD24hiCD27+ (B10)IL10+CD24hiCD38hi (immature B cells)IL10+CD38hiCD27+ (plasmablast)
value value value value value

Sex-0.0240.24-0.0180.40-0.0180.38-0.0140.870.0170.35
Age-0.0430.09-0.0910.56-0.3700.09-0.0190.62-0.0840.45
Fasting blood glucose-0.0920.13-0.0410.08-0.1320.01-0.1240.01-0.0220.19
C-peptide-0.0130.80-0.0860.230.1460.02-0.010.42-0. 0170.26
HbA1c (%)0.1310.11-0.1680.02-0.1350.03-0.15870.02-0.0560.41
ZnT8A0.0430.090.0270.420.0380.12-0.0250.910.0380.23
GADA0.0920.130.0170.280.010.780.0170.440.0240.54
IA2A0.0130.800.0120.210.0310.36-0.0450.060.0540.23

indicate significance (Pā€‰<0.05).