Research Article
Altered Regulatory B Cell Subsets in Children with Type 1 Diabetes Mellitus
Table 2
Correlations between B cell phenotypes and demographic, clinical and laboratory characteristics of the study patients.
| Variable | B cell phenotype | CD19+ total B cells | IL10+CD19+ (IL10 B cells) | IL10+CD24hiCD27+ (B10) | IL10+CD24hiCD38hi (immature B cells) | IL10+CD38hiCD27+ (plasmablast) | | value | | value | | value | | value | | value |
| Sex | -0.024 | 0.24 | -0.018 | 0.40 | -0.018 | 0.38 | -0.014 | 0.87 | 0.017 | 0.35 | Age | -0.043 | 0.09 | -0.091 | 0.56 | -0.370 | 0.09 | -0.019 | 0.62 | -0.084 | 0.45 | Fasting blood glucose | -0.092 | 0.13 | -0.041 | 0.08 | -0.132 | 0.01 | -0.124 | 0.01 | -0.022 | 0.19 | C-peptide | -0.013 | 0.80 | -0.086 | 0.23 | 0.146 | 0.02 | -0.01 | 0.42 | -0. 017 | 0.26 | HbA1c (%) | 0.131 | 0.11 | -0.168 | 0.02 | -0.135 | 0.03 | -0.1587 | 0.02 | -0.056 | 0.41 | ZnT8A | 0.043 | 0.09 | 0.027 | 0.42 | 0.038 | 0.12 | -0.025 | 0.91 | 0.038 | 0.23 | GADA | 0.092 | 0.13 | 0.017 | 0.28 | 0.01 | 0.78 | 0.017 | 0.44 | 0.024 | 0.54 | IA2A | 0.013 | 0.80 | 0.012 | 0.21 | 0.031 | 0.36 | -0.045 | 0.06 | 0.054 | 0.23 |
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indicate significance ( Pā<0.05). |