Research Article
Systematic Study of the Immune Components after Ischemic Stroke Using CyTOF Techniques
Figure 4
The surface marker expression levels of specific immune cells on corresponding cell types. The expressions of CD11c, Gr-1, CD45, CD11b, CD19, CD25, CD62L, TCR-beta, NK1.1, CD4, CD44, CD3e, CD8a, and B220 in various leukocytes, including cDC, B cell, CD8 T cell, CD4 T cell, CD8 TEM, CD4 TEM, Treg, and NK cell, in the ischemic brain, peripheral blood, spleen, and bone marrow were measured from samples of sham, day 1, day 3, day 7, and day 14 poststroke in the brain, blood, spleen, and bone marrow. The expression of CD62L has significant increases at day 7 in NK cells, CD8 T cells, microglia, and monocyte-derived macrophages (MiMØs and MoMØs) in the brain tissue.