Elevated Expression of C-Type Lectin Domain Family 5-Member A (CLEC5A) and Its Relation to Inflammatory Parameters and Disease Course in Adult-Onset Still’s Disease

Figure 1

The percentages and MFI of CLEC5A-expressing monocytes and granulocytes in patients with adult-onset Still’s disease (AOSD). Representative examples of flow cytometric histograms of CLEC5A-expressing monocytes or granulocytes obtained from peripheral blood of one active AOSD patient ((a) A) or ((b) A) and one healthy subject ((a) B) or ((b) B). Comparisons of the percentages and mean fluorescence intensity (MFI) of CLEC5A-expressing monocytes ((c) and (d)) or granulocytes ((e) and (f)) between AOSD patients and healthy control subjects. The data are presented as box-plot diagrams, in which the box encompasses the 25th percentile (lower bar) to the 75th percentile (upper bar). The horizontal line within the box indicates the median value for each group. The values were determined by using the nonparametric Mann-Whitney test.

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