Research Article

Elevated Expression of C-Type Lectin Domain Family 5-Member A (CLEC5A) and Its Relation to Inflammatory Parameters and Disease Course in Adult-Onset Still’s Disease

Table 1

The correlations between CLEC5A expression and inflammatory parameters as well as proinflammatory cytokines in 34 patients with adult-onset Still’s disease (AOSD).

CLEC5A expressionFrequency in monocyte (%)MFI in monocyteFrequency in granulocyte (%)MFI in granulocyte

Activity score0.4000.4380.3880.506
Ferritin levels (μg/l)0.3790.2710.4050.461
IL-1β levels (pg/ml)0.3610.2840.0330.245
IL-18 levels (pg/ml)0.3440.3530.3650.463

CLEC5A: C-type lectin domain family 5-member A; MFI: mean fluorescence index; IL-1β: interleukin-1β; IL-18: interleukin-18. and by the nonparametric Spearman’s rank correlation test.