Knockdown of YAP/TAZ Inhibits the Migration and Invasion of Fibroblast Synovial Cells in Rheumatoid Arthritis by Regulating Autophagy

Figure 3

Knockdown of YAP or TAZ attenuated the migration and invasion of RA-FLS. (a, c) Migration and invasion of stable YAP or TAZ knockdown RA-FLS and their corresponding control cells (shC) and null (Ctrl) were determined by wound healing assays (a) and Transwell assays (c), respectively. Representative images of three independent experiments are shown. Magnification, ×100. (b, d) Quantification of relative numbers of migrated and invaded cells in five randomly fields for each replicate was shown. All experiments were performed independently three times, and data were shown as . relative to shC by Student’s -test.

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